TIL that the organism Mycobacterium Leprae, which causes Leprosy, has never been successfully grown in a lab in non-living media. It can only be cultivated in animal specimens, specifically on armadillo feet. This makes the organism extremely difficult to study and nearly impossible to eradicate.

Read more: https://www.omicsonline.org/open-access/why-is-mycobacterium-tuberculosis-hard-to-grow-the-principle-of-biorelativity-explains-2161-0681.1000176.php?aid=26260

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